Preheat oven to 250°F. Line a baking sheet with parchment paper; set aside.
Melt butter and 1/2 tsp. salt in a small saucepan. Add sesame seeds, onion powder, garlic powder, chili powder, cumin, and paprika; cook, stirring constantly, until fragrant, about 1 minute. Remove from heat.
Place 1/3 of crackers in a medium bowl. Add 1/3 of the butter mixture, and toss to coat. Place on prepared baking sheet. Repeat procedure twice with remaining crackers and butter mixture, spreading in an even layer on baking sheet. Bake 15 minutes. Flip crackers; bake until crackers are golden brown, about 5 more minutes.
Meanwhile, add beans and remaining 1/2 tsp. salt to a food processor; process about 1 minute. Add avocados, oil, and lime juice; process until smooth, about 1 minute, scraping down sides as needed. Spoon into a serving bowl, and garnish with pomegranate seeds; serve with spiced crackers.